Biological Activities and Traditional Use of Hyptis suaveolens in Human and Veterinary Medicine: A Review
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Abstract
Hyptis suaveolens (H. suaveolens), known as Gros baume or sweet-smelling Hyptis, is an invasive plant from tropical regions widely used to manage human and animal ailments, such as bacterial, viral, and parasitic diseases. This study aimed to synthesize a scientific research work on the use of this medicinal plant in the traditional pharmacopeia, as well as the biological and pharmacological activities already recognized in the literature. Information for this synthesis was collected from physical (libraries and documentation centers of universities in Benin) and reliable scientific databases, such as PubMed, Google Scholar, Scopus, and Web of Science, which were queried based on the keywords related to H. suaveolens. This plant contains secondary metabolites in its aerial parts, such as leaves, and stems, which are rich in essential oils. From leaves to roots, all parts of this plant are of interest to both humans and animals to treat various pathologies. The most frequently cited diseases include asthma, panariasis, jaundice, hyperthermia, indigestion, stomach pains, nausea, colds, gall bladder infections, breast abscesses, hemorrhoids, oral-anal candidiasis, edemas, cramps, and skin infections The various aqueous and ethanolic extracts are evaluated by researchers and the biological activities are indicated in the literature. Those activities include the antibacterial, antifungal, larvicidal, antioxidant, anticholinesterase, insect repellent, and insecticidal effects. However, no toxicity resulting from the use of this plant has yet been reported in the literature. Research on H. suaveolens toxicity must be continued to gain a comprehensive understanding of its application in human and livestock health. This literature review allows the virtues and risks related to the traditional use of H. suaveolens in human and animal pharmacopeia. The various potentialities of this plant provide a lever for exploring its antiviral effects in traditional veterinary medicine in general.
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References
Bruselle M. Mise en place D'AMM allegée en phytothérapie vétérinaire; conséquences probable sur la pratique de la phytothérapie en médecine vétérinaire [Implementation of reduced marketing authorization for veterinary phytotherapy; probable consequences on the practice of phytotherapy in veterinary medicine]. Thèse de doctorat vétérinaire, Université de Lyon, France. 2017.
World health organization (WHO). Strategies for malaria control in the African region and steps for their implementation. Cahiers Techniques AFRO. 2013; p. 1-20.
Adjanohoun EJ, Ake Assi L, Floret JJ, Guinko S, Koumaré M, Ahyi AMR, et al. Médecine traditionnelle et pharmacopée, contribution aux études ethnobotaniques et floristiques du Mali. [Traditional medicine and pharmacopoeia, a contribution to ethnobotanical and floristic studies in Mali] 3rd ed. Paris: ACCT; 1981. p. 1 - 291.
Tamboura HH, Kaboré H, and Yaméogo SM. Ethnomédecine vétérinaire et pharmacopée traditionnelle dans le plateau central du Burkina Faso: cas de la province du Passoré. [Veterinary ethnomedicine and traditional pharmacopoeia in the central plateau of Burkina Faso: The case of the Passoré Province.] Biotechnol Agron Soc Environ. 1998; 2(3): 181-191.
Centre d'analyse des politiques economiques et sociales (CAPES). Etat des lieux des savoirs locaux au Burkina Faso. Inventaire des bonnes pratiques et propositions pour leur contribution au développement [Inventory of local knowledge in Burkina Faso. Inventory of good practices and proposals for their contribution to development]. CAPES: Ouagadougou; 2006, p. 1 - 448.
WORLD health organization (WHO). WHO traditional medicine strategy 2014-2023. Geneva: WHO; 2014-2023. p. 1-65. Availble at: https://www.who.int/publications-detail-redirect/9789241506096
WORLD health organization (WHO). Report of the WHO interregional workshop on the use of traditional medicine in primary health
care. Ulaanbaatar, Mongolia, 2007. p. 94. Availble at: https://www.who.int/publications-detail-redirect/9789241597425
Ali M, Ravinder E, and Ramachandran R. A new flavonoid from the aerial parts of Tridax procumbens. Fitoterapia. 2001; 72(3): 313-315. DOI: 10.1016/S0367-326X(00)00296-3
Zerbo P, Millogo-Rasolodimby J, Nacoulma-Ouedraogo OG, and Damme PV. Contribution à la connaissance des plantes médicinales utilisées dans les soins infantiles en pays San, au Burkina Faso [Contribution to the knowledge of medicinal plants used in infant care in San country, Burkina Faso]. Int J Biol Chem Sci. 2007; 1: 262-274. DOI: 10.4314/ijbcs.v1i3.39704
Pachkore GL, Dhale DA, and Dharasurkar AN. Antimicrobial and phytochemical screening of Hyptis suaveolens (L.Poit) Lamiaceae. Internat Multidiscipl Res J. 2011; 1(4): 1-3. Available at: https://core.ac.uk/download/pdf/236014589.pdf
Adomou AC, Yedomonhan H, Djossa B, Legba I, Oumorou M, and Akoegninou A. Etude ethnobotanique des plantes médicinales vendues dans le marché d'Abomey-Calavi au Bénin [Ethnobotanical study of medicinal plants sold in the Abomey-Calavi market in Benin]. Int J Biol Chem Sci. 2012; 6(2): 745-772. DOI: 10.4314/ijbcs.v6i2.18
Kouchadé SA, Adjatin AR, Adomou AC, Dassou HG, and Akoègninou A. Phytochimiques des plantes médicinales utilisées dans la prise en charge des maladies infantiles au Sud Bénin [Phytochemicals of medicinal plants used to treat childhood illnesses in southern Benin]. Euro Sci J. 2017; 3(1). DOI: 10.19044/esj.2016.v13n3p471
Ahoton LE, Alavo TBC, Ahomadegbe MA, Ahanhanzo C, and Agbangla C. Domestication du gros baume (Hyptis suaveolens (L.) Poit.): Techniques de production et potentiels insectes ravageurs au sud du Bénin [Domestication of coarse balsam (Hyptis suaveolens (L.) Poit.): Production techniques and potential insect pests in southern
Benin]. Int J Biol Chem Sci. 2010; 4(3): 608-614. DOI: 10.4314/ijbcs.v4i3.60463
Singh HB, and Handique AK. Antifungal activity of the essential oil of Hyptis suaveolens and its efficacy in biocontrol measures in combination with Trichoderma harzianum. J Essent Oil Res. 1997; 9: 683-687. DOI: 10.1080/10412905.1997.9700811
Sèdégan B, Akpo Y, Boko C, Attakpa E, and Alkoiret I. Perception des aviculteurs traditionnels sur la maladie de variole aviaire au sud Bénin [Traditional poultry farmers' perceptions of fowl pox in southern Benin]. Rev Mar Sci Agron Vét. 2023a; 11(1): 107-112. Available at: https://www.agrimaroc.org/index.php/Actes_IAVH2/article/view/1280/1724
Sèdégan B, Akpo Y, Boko C, Iwaka C, Attakpa E, and Alkoiret I. Méthodes chimiques et alternatives de lutte contre la variole dans les élevages de poulet : Synthèse bibliographique [Chemical and alternative control methods for smallpox on chicken farms: A literature review]. BRAB. 2023b; 33(3): 79-88. Available at: https://publications-chercheurs.inrab.bj/uploads/fichiers/recents/18027c76fc5ac2113975623f5c783d12.pdf
Toyang NJ, Wanyama J, Nuwanyakpa M, and Django S. Ethnomédecine vétérinaire: une approche pratique du traitement des maladies du bétail en afrique subsaharienne [Veterinary ethnomedicine: A practical approach to the treatment of livestock diseases in Sub-Saharan Africa]. Wageningen: Agrodok; 2007. Available at: https://duddal.org/s/bibnum-promap/item/3981
Abagli AZ, Alavo TBC, Avlessi F, and Moudachirou M. Potential of bush mint, hyptis suaveolens, essential oil for personal protection against mosquitoes bitings. J Am Mosq Control Assoc. 2012; 28(1): 15-19. DOI: 10.2987/11-6181.1
Agban A, Atchou K, Tchacondo T, Hoekou YP, Batawila K, and de Souza C. Potentiel antimicrobien des extraits de feuilles de Hyptis suaveolens poit [Antimicrobial potential of Hyptis suaveolens poit leaf extracts]. J Rech Sci Univ Lomé Série A. 2013; 15(3): 37-44. Available at: https://www.ajol.info/index.php/jrsul/article/view/121170
Nantitanon W, Chowwana PS, and Okonogi S. Antioxidant and antimicrobial activity of Hyptis suaveolens essential oil. Sci Pharm. 2007; 75: 35-36. DOI: 10.3797/scipharm.2007.75.35
Diallo D, Marston A, Terreaux C, Touré Y, Paulsen B, and Smestad HK. Screening of malian medicinal plants for antifungal, larvicidal, molluscicidal, antioxydant and radical scavenging activities. Phytother Res. 2011; 15: 401-406. DOI: 10.1002/ptr.738
Ouedraogo RL, Thiombiano N, Belem M, and Guinko S. Dynamique de l'evolution et impact d'une plante envahissante au Burkina Faso: Hyptis suaveolens (L.) poit [Evolutionary dynamics and impact of an invasive plant in Burkina Faso: Hyptis suaveolens (L.) poit]. Ann Univ Lomé (Togo), série Sciences, Tome XVIII. 2009. p. 97-115.
Grassi P, Reyesb TSU, Sosac S, Tubaroc A, Hoferd O, and Zitterl-Eglseera K. Anti-inflammatory activity of two diterpenes of hyptis suaveolens from El Salvador. Z Naturforsch C. 2006; 61(3-4): 165-170. DOI: 10.1515/znc-2006-3-402
Moreira ACP, Lima EO, Wanderley PA, Carmo ES, and de Souza EL. Chemical composition and antifungal activity of Hyptis suaveolens (L.) Poit leaves essential oil against Aspergillus species. Braz J Microbiol. 2010; 41: 28-33. DOI: 10.1590/S1517-83822010000100006
TOIL' D'EPICES. Epices, condiments et herbes aromatiques [Spices, condiments and aromatic herbs]. D'après. The plant book, 2nd ed. 2006. Available at: https://planet-vie.ens.fr/thematiques/cellules-et-molecules/molecules/epices-et-herbes-aromatiques
Johnson F, Ouossou KR, Kanko C, Tonzibo ZF, Foua-bi K, and Tano Y. Bioefficacité des Huiles Essentielles de Trois Espèces végétales (Ocimumgratissimum, Ocimum canum et Hyptis suaveolens), de la Famille des Labiees dans lalutte contre Sitophilus zeamais [Bioefficacy of essential oils of three plant species (Ocimumgratissimum, Ocimum canum and Hyptis suaveolens) of the labieae family in the fight against sitophilus zeamais]. Eur J Sci Res. 2018; 150(3): 273-284.
Soro D, Koné MW, and Kamanzi AK. Evaluation des Activités Antimicrobiennes et Anti-Radicaux Libres de Quelques Taxons Bioactifs de Côte d'Ivoire. [Evaluation of the Antimicrobial and Free Anti-Radical Activities of Selected Bioactive Taxa from Côte d'Ivoire]. Eur J Sci Res. 2010; 40(2): 307-317.
Arthur C. The evolution and classification of flowering plants. Madroño. 2077-78. Available at: https://www.biodiversitylibrary.org/part/170449
Sharma PP, Roy RK, Anurag GD, and Vipin KS. Hyptis suaveolens (L.) poit: A phyto-pharmacological review. Int J Chem Pharm Sci. 2013; 4(1): 1-11. Available at: http://www.ijcps.com/sub_pages/vol4issue1.html
Aboh BA. Phytosociologie, écologie, potentialités et aménagement des pâturages naturels envahis par Chromolaena odorata et Hyptis suaveolens en Zone Soudano-guinéenne (Bénin) [Phytosociology, ecology, potential and management of natural pastures invaded by Chromolaena odorata and Hyptis suaveolens in the Sudano-Guinean zone (Benin)]. Thèse de Doctorat, Université d'Abomey-Calavi, Bénin. 2008. Available at : http://www.slire.net/document/1625
Soumahoro B, Soro Y, Kassi ABB, and Siaka S. Etude comparative des caractéristiques phytochimiques des feuilles de Hyptis suaveolens avant et après extraction de l'huile essentielle [Comparative study of the phytochemical characteristics of Hyptis suaveolens leaves before and after extraction of the essential oil]. J Soc Ouest-Afr Chim. 2020; 49: 1-8. Available at : https://www.soachim.info/document/journal-soachim/article/Vol-049Num-1-f9c453dc515f01983959ccc4f0643fac.pdf
Goly KRC, Soro Y, Dadié A, Kassi ABB, and Djé M. Antibacterial activity of essential oils and extracts from the leaves of Hyptis suaveolens and Lippia multiflora on multi-resistant bacteria. Rasayan J Chem. 2015; 8(4): 396-403. Available at: https://rasayanjournal.co.in/vol-8/issue-4/1_Vol.8,%20No.4,%20396-403,%20Oct.-Dec.,%202015,%20RJC%201345.pdf
Kumar SN, and Thampi N. Phytochemical screening and characterization of the bioactive compounds from the leaves of Hyptis suaveolens and Spathodea campanulata. J Chem Pharm Res. 2015; 7(7): 840-850.
Tia EV, Adima AA, Niamké SL, Jean GA, Martin T, Lozano P, et al. Chemical composition and insecticidal activity of essential oils of two aromatic plants from Ivory Coast against Bemisia tabaci G. (Hemiptera: Aleyrodidae). Nat Prod Commun. 2011; 6(8): 1183- 1188. DOI: 10.1177/1934578X1100600835
Mandal SM, Mondal KC, Dey S, and Pati BR. Antimicrobial activity of the leaf extracts of Hyptis suaveolens (L.) poit. Indian J Pharm Sci. 2007; 69(4): 568-569. DOI: 10.4103/0250-474X.36946
Jaenson TGT, Palsson K, and Borg-Karlson AK. Evaluation of extracts and oils of mosquito (Diptera : Culicidae) repellent plants from Sweden and Guinea-Bissau. J Med Entomol. 2006; 43(1) :113-119. DOI: 10.1093/jmedent/43.1.113
Peerzada N. Chemical composition of the essential oil of Hyptis suaveolens. Int J Molecules. 1997; 2: 165-168. DOI: 10.3390/21100165
Koné MD. Etude de la phytochimie et des activités larvicide, anticholinesterasique et antioxydante des extraits de quatre plantes du Mali : Acacia nilotica Guill. et Perr. (Mimosaceae), Calotropis procera (Ait.) Ait.f. (Asclepiadaceae), Euphorbia sudanica A. Chev (Euphorbiaceae) et Hyptis suaveolens (L.) Poit (Lamiaceae) [Study of the phytochemistry and larvicidal, anticholinesterase and antioxidant activities of extracts from four plants from Mali: Acacia nilotica Guill. et Perr. (Mimosaceae), Calotropis procera (Ait.) Ait.f. (Asclepiadaceae), Euphorbia sudanica A. Chev (Euphorbiaceae) and Hyptis suaveolens (L.) Poit (Lamiaceae)]. Thèse de doctorat. Année University, France. 2009. Available at: https://bibliosante.ml/handle/123456789/7082?locale-attribute=en
Islam AKMM, Ohno O, Suenaga K, and Kato-Noguchi H. Suaveolic acid: A potent phytotoxic substance of hyptis suaveolens. Sci World J. 2014; 2014: 425942. DOI: 10.1155/2014/425942
Azevedo NR, Campos IF, Ferreira HD, Portes TA, Santos SC, Seraphin JC, et al. Chemical variability in the essential oil of Hyptis suaveolens. Phytochemistry. 2001; 57(5): 733-736. DOI: 10.1016/S0031-9422(01)00128-5
Fun CE, and Svendsen AB. The essential oil of Hyptis suaveolens Poit. grown on Aruba. Flav Fragr J. 1990; 5: 161-163. DOI: 10.1002/ffj.2730050306
Koudokpon H, Dougnon VT, Bankolé HS, Fah L, Hounmanou YMG, Baba-moussa L, et al. Enquête ethnobotanique sur les plantes utilisées dans le traitement des infections au Sud-Bénin [Ethnobotanical survey of plants used to treat infections in southern Benin]. Health Sci Dis. 2017; 18(2): 92-99. Available at: http://www.hsd-fmsb.org/index.php/hsd/article/view/809/pdf_436
Tano DK, Christian NOR, N'Guessan AP, Obodji A, N'Guessan Y, and Lucie ALRN. Effet insecticide des extraits aqueux de deux plantes sur hellula undalis fabricius, 1781 (Lepidoptera: Pyralidae), ravageur de la culture de chou brassica oleracea L. (Daloa, Côte d'Ivoire) [Insecticidal effect of aqueous extracts of two plants on hellula undalis fabricius, 1781 (Lepidoptera: Pyralidae), pest of cabbage crop brassica oleracea L. (Daloa, Ivory Coast)]. Eur J Sci Res. 2019; 2(10) : 168-180.
Sane. Efficacité biologique des extraits d'Azadirachta indica A. Juss, Hyptis suaveolens (L.) Poit et Anacardium occidentale Linn. dans la lutte contre Helicoverpa armigera (Hübner, 1808) (Lepidoptera, Noctuidae) ravageur du cotonnier (Gossypium hirsutum L.) au Sénégal [Biological efficacy of extracts of Azadirachta indica A. Juss, Hyptis suaveolens (L.) Poit and Anacardium occidentale Linn. in the control of Helicoverpa armigera (Hübner, 1808) (Lepidoptera, Noctuidae) pest of cotton (Gossypium hirsutum L.) in Senegal]. Thèse de doctorat en Entomologie Université Cheikh Anta Diop de Dakar. 2021.
Seyoum A, Kabiru EW, Lwande W, Killeen GF, Hassanali A, and Knols BG. Repellency of live potted plants against Anopheles gambiae from human baits in semi-field experimental huts. Am J Trop Med Hyg. 2002; 67(2) : 191-195. DOI: 10.4269/ajtmh.2002.67.191
Kerharo J, and Adam JG. La pharmacopée sénégalaise traditionnelle : plantes médicinales et toxiques [Traditional Senegalese pharmacopoeia: Medicinal and toxic plants]. Journal d'agriculture traditionnelle et de botanique appliquée. 1974 ; 21(1-3): 76-77. Available at: https://www.persee.fr/doc/jatba_0021-7662_1974_num_21_1_3153_t1_0076_0000_2
Byavu N, Henrard C, Dubois M, and Malaisse F. Phytothérapie traditionnelle des bovins dans les élevages de la plaine de la Ruzizi [Traditional herbal medicine for cattle on the Ruzizi plain].
Agron Soc Environ. 2000; 4(3): 135-156. Available at : https://popups.uliege.be/1780-4507/index.php?id=15244
Pachkore GL, Dhale DA, and Dharasurkar AN. Antimicrobial and phytochemical screening of Hyptis suaveolens (L.Poit) Lamiaceae. Internat Multidiscipl Res J. 2011; 1(4): 1-3. Available at: https://core.ac.uk/download/pdf/236014589.pdf
Chitra S, Patil MB, and Ravi k. Wound healing activity of hyptis suaveolens (L.) Poit (Lamiaceae). Int J Pharm Tech Res. 2009; 1(3): 737-744.
de Souza C, Ameganvi KK, Koumaglo K, and Gbeassor M. Etude de l'activité antimicrobienne des extraits aqueux totaux de dix plantes médicinales [Study of the antimicrobial activity of total aqueous extracts of ten medicinal plants]. PMTA . 1993; 2(7): 107-115.
Rojas A, Hernandez L, Pereda-Miranda R, and Mata R. Screening for antimicrobial activity of crude drug extracts and pure natural products from Mexican medicinal plants. J Ethnopharmacol. 1992; 35(3): 75-83. DOI: 10.1016/0378-8741(92)90025-M
Mbatchou VC, Abdullatif S, and Glover R. Phytochemical screening of solvent extracts from Hyptis suaveolens Lam for fungal growth inhibition. Pak J Nutr. 2010; 9(4): 358-361. DOI: 10.3923/pjn.2010.358.361
Bah S. Sensibilité de Anopheles gambiae aux insecticides organiques de synthèse et à divers extraits de plantes médicinales du Mali [Sensitivity of Anopheles gambiae to synthetic organic insecticides and various medicinal plant extracts from Mali]. Thèse de Doctorat en Pharmacie, University of Bamako, Mali. 1998. Available at: https://bibliosante.ml/handle/123456789/12017?show=full
Aouinty B, Oufara S, Mellouki F, and Mahari S. Evaluation préliminaire de l'activité larvicide des extraits aqueux des feuilles de Ricinus communis L. et du bois de Tetraclinis articulata (Vahl) Mast. sur les larves de quatre moustiques culicidés : Culex pipiens (Pallas), Culiseta longiareolata (Aitken) et Anopheles maculipennis [Preliminary evaluation of the larvicidal activity of aqueous extracts of Ricinus communis L. leaves and Tetraclinis articulata (Vahl) Mast. wood on the larvae of four culicid mosquitoes: Culex pipiens (Pallas), Culiseta longiareolata (Aitken) and Anopheles maculipennis]. (Meigen). Biotechnol Agron Soc Environ. 2006; 10(2): 67-71. Available at: https://www.cabidigitallibrary.org/doi/full/10.5555/20063124498
Diakité B. La susceptibilité des larves de Anopheles gambiae s.l. à des extraits de plantes médicinales du Mali [The susceptibility of larvae of Anopheles gambiae s.l. to medicinal plant extracts from Mali]. Thèse de Doctorat en Pharmacie, University of Bamako, Mali. 2008. Available at: https://bibliosante.ml/bitstream/handle/123456789/8282/08M147.pdf?sequence=1
Sharma N, Quadry JS, Subrabanium B, Verghese T, Rahman SS, Sharma SK, et al. Larvicidal activity of Gliricidia sepium against mosquito larvae of Anopheles stephansi, Aedes aegypti and Culex quinquefaciatus [Larvicidal activity of Gliricidia sepium against mosquito larvae of Anopheles stephansi, Aedes aegypti and Culex quinquefaciatus] . Pharm Biol. 1998; 36(1): 3-7. DOI: 10.1076/phbi.36.1.3.4616
Houghton PJ, Agbedakunsi JM, and Adegbulugbe A. Cholinesterase inhibitory properties of alkaloids from two Nigerian Crinum species. Phytochemistry. 2004; 65(21): 2893-2896. DOI: 10.1016/j.phytochem.2004.08.052
Ferreira A, Proença C, Serralheiro MLM, and Araùjo MEM. The in vitro screening for acetylcholinesterase inhibition and antioxydant activity of medicinal plants from Portugal. J Ethnopharmacol. 2006; 108: 31-37. DOI: 10.1016/j.jep.2006.04.010
Pincemail J, Meurisse M, Limet R, and Defraigne J. Méthodes d'évaluation du stress antioxydant chez l'homme: Importance en matière de prévention. Cancérologie Ed Medi Sphere [Methods for assessing antioxidant stress in humans: Importance in prevention. Oncology Ed Medi Sphere]. 1999.
Bruneton J. Pharmacognosie et phytochimie des plantes médicinales [Pharmacognosy and phytochemistry of medicinal plants]. 2nd ed. Paris: Lavoisier ; 1993.
Cavin A. Investigation phytochimique des trois plantes indonésiennes aux propriétés antioxydantes et antiradicalaires: Tinospora crisa (Menispernaceae), Merremia emarginata (Convovulaceae) et Orephea eneandra (Annonaceae) [Phytochemical investigation of three Indonesian plants with antioxidant and free radical scavenging properties: Tinospora crisa (Menispernaceae), Merremia emarginata (Convovulaceae) and Orephea eneandra (Annonaceae)]. -Thèse de doctorat, Année University, France. 1999. https://bibliosante.ml/bitstream/handle/123456789/6828/05P21.pdf?sequence=1
Fiol M, Adermann S, Neugart S, Rohn S, Mügge C, Schreiner M, et al. Highly glycosylated and acylated flavonols isolated from kale (Brassica oleracea var. sabellica) - Structure -antioxidant activity relationship. Food Res Int. 2012; 47: 80-89. DOI: 10.1016/j.foodres.2012.01.014
Kossou KD, Gbehounou G, Bouraima Y, Huis A, Ahanchede A, Ahohuendo B, et al. Extrait aqueux de Hyptis suaveolens plante nouvellement identifiée au Bénin pour le contrôle des insectes nuisibles du niébé au champ [Aqueous extract of Hyptis suaveolens, a plant newly identified in Benin, for the control of insect pests of cowpea in the field]. Projet Niébé BJ 002906, Bénin. 2000. p. 32.
Ngom S, Perez RC, Mbow MA, Fall R, Niassy S, Cosoveanu A, et al. Larvicidal activity of Neem oil and three plant essential oilsfrom Senegal against Chrysodeixis chalcites (Esper, 1789). Asian Pac J Trop Biomed. 2018; 8(1): 67-72. DOI: 10.4103/2221-1691.221140
Cherry R, and Nuessly G. Repellency of the biopesticide, Azadirachtin, to wireworms (Coleoptera: Elateridae). Fla Entomol. 2010; 93(1): 52-55. DOI: 10.1653/024.093.0107
Attawish A, Chivapat S, Chavalittumrong P, Phadungpat S, Bandiddhi J, and Chaorai B. Chronic toxicity study of Hyptis suaveolens (L.) Poit in rats. Songklanakarin J Sci Technol. 2005; 27(5): 1027-1036.
Azeez OM, and Pitan OOR. Sole and combined effect of three botanicals against cowpea seed bruchid, Callosobruchus maculatus Fabricius. Afr J Agric Res. 2018; 13(7): 321-328. DOI: 10.5897/AJAR2017.12737
Belder Den E, Elderson J, and Agca I. Host finding of thrips tabaci disrupted by volatiles. Department of Crop Production Ecology, Wageningen University, Netherlands, 1998.
Ngamo TSL, Ngatanko I, Ngassoum MB, Mapongmestsem PM, and Hance T. Persistence of insecticidal activities of crude essential oils of three aromatic plants towards four major stored product insect pests. Afr J Agric Res. 2007; 2(4): 173-177. Available at: https://academicjournals.org/journal/AJAR/article-full-text-pdf/491C5DE30606
Conti B, Canale A, Cioni PL, Flamini G, and Rifici A. Hyptis suaveolens and Hyptis spicigera (Lamiaceae) essential oils: qualitative analysis, contact toxicity and repellent activity against Sitophilus granarius (L.) (Coleoptera: Dryophthoridae). J Pest Sci. 2011; 84: 219-228. DOI: 10.1007/s10340-010-0343-0
Guèye MT, Diallo A, Guèye S, Seck D, Assiedu E, Wathelet JP, et al. Analysis of the composition of plant essential oil used in cereals and legumes storage in Senegal. J Essent Oil Bear Pl. 2016 ; 19(2) : 403-409. DOI: 10.1080/0972060X.2014.935019
Gbedomon CR, Sikirou R, Zannou E, Pomalegni SCB, Goergen G, Bokonon-Ganta H, et al. Extraits botaniques utilisés contre les arthropodes associés aux abeilles et produits de la ruche inventoriés dans les ruchers au centre du Bénin [Botanical extracts used against bee-associated arthropods and hive products inventoried in apiaries in central Benin]. Actes du 3ème Colloque des Sciences, Cultures et Technologies de l'UAC-Bénin, 2012; pp. 573-588.
Adda C, Atachi P, Hell K, and Tamo M. Potential use of the bushmint, Hyptis suaveolens, for the control of infestation by the pink stalk borer, Sesamia calamistis on maize in southern Benin, West Africa. J Insect Sci. 2011; 11(1): 33. DOI: 10.1673/031.011.0133
Agboka K, Agbodzavu KM, Tomò M, and Vidal S. Effects of plant extracts and oil emulsions on the maize cob borer Mussidia nigrivenella (Lepidoptera: Pyralidae) in laboratory and field experiments. Int J Trop Insect Sci. 2009; 29(4): 185-194. DOI: 10.1017/S1742758409990348
Tounou AK, Sokame BM, Akpavi S, Ganyo KK, Ketoh KG, and Gumedzoe YMD. Effets des extraits végétaux sur la dynamique de populations des insectes ravageurs de niébé, vigna unguiculata Walp, dans le sud du Togo [Effects of plant extracts on the population dynamics of insect pests of
cowpea, vigna unguiculata Walp, in southern Togo]. J Rech Sci Univ Lomé. 2012; 14(1): 25-34. Available at: https://www.ajol.info/index.php/jrsul/article/view/86754#:~:text=Des%20r%C3%A9sultats%20de%20cette%20%C3%A9tude,ni%C3%A9b%C3%A9%20en%20condition%20de%20champ
Ahmad J, Khan I, Ahmad A, and Imam K. In Vitro antioxidant and antimicrobial activity of methanolic root extracts of Hyptis suaveolens. Res J Recent Sci. 2013; 2: 41-46. Available at: http://www.isca.in/rjrs/archive/v2/iISC-2012/9.ISCA-ISC-2012-03BS-85.php
Shaikat ZH, Hossain T, and Azam G. Phytochemical screening and antidiarrhoeal activity of Hyptis suaveolens. Int J Appl
Res Nat Prod. 2012; 5(2): 1-4. Available at: https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=e2fe598b586af0d1897457a4228412fd8479cf9d
Praveen Nayak S, Nayak S, Kar DM, and Das P. In vitro antihelmintic activity of whole plant extracts of Hyptis suaveolens Poit. Int J Curr Pharm Res. 2010; 2(2): 5051.
Boni BY, Komlan AF, Mensah A, Taofic A, Verheggen F, and Frédéric F. Plantespesticides et protection des cultures maraichères en Afrique de l'Ouest (synthèse bibliographique) [Pesticide plants and protection of market garden crops in West Africa (literature review)]. Biotechnol Agron Soc Environ. 2017; 21(4): 288-304. DOI: 10.25518/1780-4507.16175